The association between parental SARS-CoV-2 infection in pregnancy and fetal growth restriction.
In: Journal of Perinatal Medicine, Jg. 52 (2024-03-01), Heft 3, S. 317-321
academicJournal
Zugriff:
Although the relationship between maternal viral infections and fetal growth restriction (FGR) is well established, the association between SARS-CoV-2 infection in pregnancy and FGR remains unclear. We investigated the association between SARS-CoV-2 infection in pregnancy and FGR at a single county hospital. We performed a prospective cohort study with cohorts matched by gestational age and month of SARS-CoV-2 PCR testing between April 2020 and July 2022. Individuals were included if they had a SARS-CoV-2 PCR testing up to 32 weeks of gestation and had a third trimester ultrasound. Primary outcome was a diagnosis of FGR, while secondary outcomes were rates of preeclampsia, small for gestational age (SGA) and birthweight. Univariate analyses, chi-square test and logistic regression were used for analysis. Our cohorts constituted of 102 pregnant individuals with a positive SARS-CoV-2 PCR test result and 103 pregnant individuals with a negative SARS-CoV-2 PCR test result in pregnancy. FGR rates were 17.8 % and 19.42 % among positive and negative SARS-CoV-2 cohorts respectively. While a statistical difference in preeclampsia rates was noted (34.31 % vs. 21.36 %, p=0.038) between cohorts, odds of getting preeclampsia based on SARS-CoV-2 test result was not significant (aOR 1.01, CI=0.97–1.01, p=0.75). No statistical difference was noted in demographics, FGR and SGA rates, and birthweight. Our findings suggest no association between SARS-CoV-2 infection in pregnancy and FGR at a single institution. Our results validate emerging data that additional fetal growth ultrasonographic assessment is not indicated solely based on SARS-CoV-2 infection status. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Perinatal Medicine is the property of De Gruyter and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
The association between parental SARS-CoV-2 infection in pregnancy and fetal growth restriction.
|
---|---|
Autor/in / Beteiligte Person: | Mitta, Melanie ; Holt, Lauren ; Chandrasekaran, Suchitra ; Dude, Carolynn |
Zeitschrift: | Journal of Perinatal Medicine, Jg. 52 (2024-03-01), Heft 3, S. 317-321 |
Veröffentlichung: | 2024 |
Medientyp: | academicJournal |
ISSN: | 0300-5577 (print) |
DOI: | 10.1515/jpm-2023-0406 |
Schlagwort: |
|
Sonstiges: |
|