Characterization of mutational "coldspots" in the cancer genome.
In: Blood Weekly, 2024-04-25, S. 136-136
serialPeriodical
Zugriff:
A recent study published in Nucleic Acids Research by researchers at the Institute for Research in Biomedicine (IRB Barcelona) has identified "coldspots" in the cancer genome where mutation rates are lower than usual. These coldspots have been linked to low DNA methylation, an epigenetic mark, which provides insight into their regulation. Understanding the distribution of mutation rates could lead to the development of targeted therapies to protect specific genomic regions and diagnostic tools to monitor these regions, potentially preventing the accumulation of mutations that drive cancer development or progression. This research was funded by the European Research Council and the Spanish Ministry of Science and Innovation. [Extracted from the article]
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Characterization of mutational "coldspots" in the cancer genome.
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Zeitschrift: | Blood Weekly, 2024-04-25, S. 136-136 |
Veröffentlichung: | 2024 |
Medientyp: | serialPeriodical |
ISSN: | 1065-6073 (print) |
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