Risk Factors for Treatment Failure in Neonates With Skin and Soft Tissue Infection: A Retrospective Cohort Study.
In: Clinical Pediatrics, Jg. 63 (2024-06-01), Heft 5, S. 689-696
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Zugriff:
We aimed to describe the frequency of treatment failure and associated risk factors for treatment failure amongst neonates with skin and soft tissue infections (SSTIs). We conducted a retrospective cohort study of neonates 0 to 28 days old with uncomplicated SSTIs presenting to the emergency department of a quaternary care children's hospital from 2009 to 2017. Data were collected via chart review. Skin and soft tissue infections included the following: cellulitis, abscess, mastitis, perirectal SSTI, carbuncle, and furuncle. Of the 202 neonates in the study, most were term, afebrile with mastitis, or perirectal SSTI. Treatment failure occurred in 8% (17/202) of neonates receiving oral antibiotics; 10 of these neonates had perirectal SSTIs and 2 had clindamycin and methicillin-resistant Staphylococcus aureus. Neonates with treatment failure had increased odds of having perirectal SSTIs (odds ratio [OR] = 4.08, 95% confidence interval [CI] = 1.46-11.31). Further studies are needed to identify strategies to prevent treatment failure in neonates with perirectal SSTIs. [ABSTRACT FROM AUTHOR]
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Titel: |
Risk Factors for Treatment Failure in Neonates With Skin and Soft Tissue Infection: A Retrospective Cohort Study.
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Autor/in / Beteiligte Person: | Patel, Purva ; Foster, Catherine E. ; Stimes, Grant ; Lee, Su Rin ; Wallace, Sowdhamini S. |
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Zeitschrift: | Clinical Pediatrics, Jg. 63 (2024-06-01), Heft 5, S. 689-696 |
Veröffentlichung: | 2024 |
Medientyp: | academicJournal |
ISSN: | 0009-9228 (print) |
DOI: | 10.1177/00099228231189132 |
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