Investigating the effect of Aloe vera on the prevention and treatment of radiotherapy-induced oral mucositis in patients with head-and-neck cancer.
In: Journal of Research in Medical Sciences, Jg. 29 (2024-03-01), S. 1-7
Online
academicJournal
Zugriff:
Background: Oral mucositis is one of the main complications of radiotherapy (RT) while treating head-and-neck cancers and can affect the patients' treatment process and life. Therefore, this study evaluated the effect of Aloe vera on the prevention and treatment of radiotherapy-induced oral mucositis (RIOM) in patients with head-and-neck cancer. Materials and Methods: This was a double-blind clinical trial performed in 2019 on 75 patients with head-and-neck cancer. Patients were randomly assigned to two groups receiving gargles of 5 cc Aloe vera and the same dose of placebo mouthwash three times a day, respectively. Then, the incidence and severity of RIOM were evaluated and compared between the two groups over 6 weeks of RT. Results: There was no significant difference between the two groups in terms of the severity of RIOM from the 1 st to 3 rd weeks of RT (P > 0.05). However, the severity of RIOM in the 4 th , 5 th , and 6 th weeks of RT was significantly lower in the Aloe vera group compared with the placebo group (P < 0.05). Conclusion: According to the results of the present study, the long-term use of Aloe vera mouthwash can reduce the severity of RIOM. [ABSTRACT FROM AUTHOR]
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Titel: |
Investigating the effect of Aloe vera on the prevention and treatment of radiotherapy-induced oral mucositis in patients with head-and-neck cancer.
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Autor/in / Beteiligte Person: | Najafizade, Nadia ; Dehkordi, Roya Mobini ; Hemati, Simin |
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Zeitschrift: | Journal of Research in Medical Sciences, Jg. 29 (2024-03-01), S. 1-7 |
Veröffentlichung: | 2024 |
Medientyp: | academicJournal |
ISSN: | 1735-1995 (print) |
DOI: | 10.4103/jrms.jrms_115_23 |
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