三级淋巴组织在急性肾损伤慢性化转归中的研究进展. (Chinese)

Acute kidney injury (AKI) is characterized by a rapid decline in glomerular filtration rate, which is an important risk factor for the occurrence and development of chronic kidney disease (CKD). A thorough understanding of this process is helpful to prevent AKI from progressing to CKD. Tertiary lymphoid tissues (TLTs) are formed by the aggregation of lymphocytes in non-lymphoid organs, which play a role in kidney diseases. This article reviewed the molecular mechanism of TLTs formation, the role of TLTs in the development of AKI to CKD. and the targeted therapeutic strategies. [ABSTRACT FROM AUTHOR]

急性肾损伤(AKI)以肾小球滤过率快速下降为特点,是慢性肾脏病(CKD)发生和发展的重要 危险因素,深入了解这一过程有助于阻止 AKI向 CKD 进展。三级淋巴组织(TLTs)是由淋巴细胞在非淋巴器 官内聚集形成,在肾脏疾病中发挥作用。该文对 TLTs形成的分子机制、TLTs在 AKI向 CKD 发展的作用及 治疗策略进行了综述。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)