Findings from Pennsylvania State University (Penn State) Provides New Data on Opioids (Coexpressed D-, L-, and J-opioid Receptors Modulate Voltagegated Ca2+channels In Gastric-projecting Vagal Afferent Neurons).
In: Drug Week, 2024-06-07, S. 734-734
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Zugriff:
A recent study conducted by researchers at Pennsylvania State University (Penn State) investigated the effects of opioids on gastric motility and emptying. The study found that opioids can modulate gastric vagal circuits, which may contribute to gastrointestinal side effects such as constipation and reduced gastric motility. The researchers used whole-cell patch-clamp recordings to determine the mechanism by which opioid receptors affect calcium currents in gastric vagal afferent neurons. The findings suggest that analgesics targeting any opioid receptor subtype can impact gastric vagal circuits. This research was funded by the NIH and has been peer-reviewed. [Extracted from the article]
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Findings from Pennsylvania State University (Penn State) Provides New Data on Opioids (Coexpressed D-, L-, and J-opioid Receptors Modulate Voltagegated Ca2+channels In Gastric-projecting Vagal Afferent Neurons).
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Zeitschrift: | Drug Week, 2024-06-07, S. 734-734 |
Veröffentlichung: | 2024 |
Medientyp: | serialPeriodical |
ISSN: | 1531-6440 (print) |
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