Towards Personalized Medicine in Rheumatoid Arthritis.
In: Open Access Rheumatology: Research & Reviews, Jg. 16 (2024-05-01), S. 89-114
Online
academicJournal
Zugriff:
Rheumatoid arthritis (RA) is a chronic, incurable, multisystem, inflammatory disease characterized by synovitis and extra-articular features. Although several advanced therapies targeting inflammatory mechanisms underlying the disease are available, no advanced therapy is universally effective. Therefore, a ceiling of treatment response is currently accepted where no advanced therapy is superior to another. The current challenge for medical research is the discovery and integration of predictive markers of drug response that can be used to personalize medicine so that the patient is started on "the right drug at the right time". This review article summarizes our current understanding of predicting response to anti-rheumatic drugs in RA, obstacles impeding the development of personalized medicine approaches and future research priorities to overcome these barriers. [ABSTRACT FROM AUTHOR]
Copyright of Open Access Rheumatology: Research & Reviews is the property of Dove Medical Press Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Towards Personalized Medicine in Rheumatoid Arthritis.
|
---|---|
Autor/in / Beteiligte Person: | Sharma, Seema D ; Bluett, James |
Link: | |
Zeitschrift: | Open Access Rheumatology: Research & Reviews, Jg. 16 (2024-05-01), S. 89-114 |
Veröffentlichung: | 2024 |
Medientyp: | academicJournal |
ISSN: | 1179-156X (print) |
DOI: | 10.2147/OARRR.S372610 |
Schlagwort: |
|
Sonstiges: |
|