Venous Thrombosis Recurrence After Catheter-Related Upper Extremity Deep Venous Thrombosis in Cancer Patients: A Retrospective Analysis.
In: Angiology, Jg. 75 (2024-08-01), Heft 7, S. 658-665
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Zugriff:
Long-term indwelling central venous catheters (CVC) are frequently used to secure vascular access to deliver injectable treatment. Catheter-related thrombosis (CRT) occurs in approximately 2–6% of cancer patients. We conducted a single-center retrospective study to assess the rate of venous thromboembolism (VTE) recurrence in cancer patients; 200 patients were included. Mean age was 56 ± 15.15 years, median follow-up duration was 16.5 [range: 10–36] months. The incidence of recurrence was estimated using Gray's method for competing risk with death as the competing event of VTE. Recurrent VTE occurred in 25.5% of patients with a median occurrence time of 6.5 [range: 5–11.25] months. In case of recurrence, 94.6% of patients were treated for cancer and 80.4% of them received anticoagulants; 4 major bleeds and 17 non-major bleeds occurred during follow-up. In multivariate analysis, previous VTE (Hazard Ratio (HR) 2.48 (95% CI 1.42–4.32) and presence of CVC (HR 5.56 (95% CI 1.96–15.75) were significant recurrence risk factors. After a first episode of CRT, 25.5% of patients experienced VTE recurrence as UEDVT in 30 cases (55.5%), PE in 17 cases (31.5%), and DVT in 7 cases (13%), mostly during anticoagulation therapy. Anticoagulation therapy does not avoid CRT in case of cancer and must be balanced with hemorrhagic risk. [ABSTRACT FROM AUTHOR]
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Titel: |
Venous Thrombosis Recurrence After Catheter-Related Upper Extremity Deep Venous Thrombosis in Cancer Patients: A Retrospective Analysis.
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Autor/in / Beteiligte Person: | Hakem, Rabiaa ; Soudet, Simon ; Diouf, Momar ; Sevestre, Marie Antoinette |
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Zeitschrift: | Angiology, Jg. 75 (2024-08-01), Heft 7, S. 658-665 |
Veröffentlichung: | 2024 |
Medientyp: | academicJournal |
ISSN: | 0003-3197 (print) |
DOI: | 10.1177/00033197231176985 |
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