Efficacy and Safety of Pyridoxal 5'-Phosphate (MC-1) in High-Risk Patients Undergoing Coronary Artery Bypass Graft Surgery.
In: JAMA: Journal of the American Medical Association, Jg. 299 (2008-04-16), Heft 15, S. 1777-1787
academicJournal
Zugriff:
The article focuses on a study testing the effectiveness and safety of the naturally occurring pyridoxine metabolite and purinergic receptor antagonist MC-1 given to patients undergoing coronary artery bypass graft (CABG) surgery. The objective of the trial was to reduce morbidity and mortality rates in CABG patients due to common complications related to ischemia-reperfusion injury and myocardial infarction (MI). Researchers concluded that MC-1 did not reduce cardiovascular death or nonfatal MI among intermediate to high-risk patients undergoing CABG surgery.
| Titel: |
Efficacy and Safety of Pyridoxal 5'-Phosphate (MC-1) in High-Risk Patients Undergoing Coronary Artery Bypass Graft Surgery.
|
|---|---|
| Autor/in / Beteiligte Person: | Alexander, John H. ; Emery Jr, Robert W. ; Carrier, Michel ; Ellis, Stephen J. ; Mehta, Rajendra H. ; Hasselblad, Vic ; Menasche, Philippe ; Khalil, Ahmad ; Cote, Robert ; Bennett-Guerrero, Elliot ; Mack, Michael J. ; Schuler, Gerhard ; Harrington, Robert A. ; Tardif, Jean-Claude |
| Zeitschrift: | JAMA: Journal of the American Medical Association, Jg. 299 (2008-04-16), Heft 15, S. 1777-1787 |
| Veröffentlichung: | 2008 |
| Medientyp: | academicJournal |
| ISSN: | 0098-7484 (print) |
| DOI: | 10.1001/jama.299.15.joc80027 |
| Schlagwort: |
|
| Sonstiges: |
|