Primary care-based surveillance to estimate the burden of rotavirus gastroenteritis among children aged less than 5 years in six European countries.
In: European Journal of Pediatrics, Jg. 170 (2011-02-01), Heft 2, S. 213-222
Online
academicJournal
Zugriff:
This observational, prospective study was undertaken to estimate the burden of rotavirus (RV) gastroenteritis (GE) leading to general practitioner (GP)/family paediatrician (FP) visits among children aged <5 years in Czech Republic, Germany, Italy, Poland, Spain and the UK. Children aged <5 years presenting with acute GE provided stool samples for rapid RV testing. RV+ samples were confirmed and typed by RT-PCR. Demographic and clinical data were collected for all RVGE episodes. Transmission patterns among other household children aged <5 years were also assessed. From November 2005 to May 2007, excluding data from the UK, 497/3,813 (13.0%) children aged <5 years presenting with acute GE to GP/FP and tested were RV+ by PCR. Most RVGE cases (69.1%) occurred in children aged <2 years, occurred between December and May (93.1%) and were moderate or severe by Vesikari score (92.9%). RV strain distribution varied between countries: G9P[8] was the most common type in Poland (54/76) and Spain (172/196), G1P[8] was predominant in the Czech Republic (56/64) and Italy (46/107), and G4P[8] and G1P[8] both prevailed in Germany (17/54 and 13/54, respectively). A total of 24/122 (19.7%) children aged <5 years resident in the same household as a PCR+ study participant also developed RVGE. Conclusion. This multinational epidemiological study in Europe shows that RV is easily transmitted among household children, with RVGE burden highest among children aged <2 years accessing primary healthcare for acute GE. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Pediatrics is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Primary care-based surveillance to estimate the burden of rotavirus gastroenteritis among children aged less than 5 years in six European countries.
|
---|---|
Autor/in / Beteiligte Person: | Diez-Domingo, Javier ; Baldo, Jose-Maria ; Patrzalek, Marian ; Pazdiora, Petr ; Forster, Johannes ; Cantarutti, Luigi ; Pirçon, Jean-Yves ; Soriano-Gabarró, Montse ; Meyer, Nadia ; SPRIK Rotavirus Study Group |
Link: | |
Zeitschrift: | European Journal of Pediatrics, Jg. 170 (2011-02-01), Heft 2, S. 213-222 |
Veröffentlichung: | 2011 |
Medientyp: | academicJournal |
ISSN: | 0340-6199 (print) |
DOI: | 10.1007/s00431-010-1289-1 |
Schlagwort: |
|
Sonstiges: |
|