Maternal preeclampsia is associated with an increased risk of retinopathy of prematurity.
In: Journal of Perinatal Medicine, Jg. 39 (2011-09-01), Heft 5, S. 523-527
Online
academicJournal
Zugriff:
Objective: To determine the effect of maternal preeclampsia on development and severity of retinopathy of prematurity (ROP) in preterm infants. Methods: This prospective study consisted of two groups: the study group, which is composed of preterm infants (≤32 weeks) born to a mother with preeclampsia, and the comparison group, which is composed of preterm infants (≤32 gestational age) born to normotensive mothers. We used the International Classification of Retinopathy of Prematurity Revisited for classifying ROP. The first eye examination was performed at postnatal age of 4 weeks. Results: A total of 385 infants were included in the study. ROP was diagnosed in 109 infants (28%). The incidence of ROP in infants born to preeclamptic mothers (40.5%) was significantly higher compared with those born to normotensive mothers (22.4%) (P<0.05). The number of infants with stage 1, 2, and 3 ROP was significantly higher in infants born to preeclamptic mothers compared with the control group (P<0.05). In multiple logistic regression model, preeclampsia was found to predict ROP (odds ratio 1.78, 95% confidence interval 0.66-1.90). Conclusion: Maternal preeclampsia was found to be associated with increased ROP development risk in premature infants. ROP was also more severe in infants born to pre-eclamptic mothers. The role of maternal preeclampsia in the occurrence and severity of ROP remains to be elucidated. [ABSTRACT FROM AUTHOR]
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Titel: |
Maternal preeclampsia is associated with an increased risk of retinopathy of prematurity.
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Autor/in / Beteiligte Person: | Özkan, Hilal ; Cetinkaya, Merih ; Koksal, Nilgun ; Özmen, Ahmet ; Yıldız, Meral |
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Zeitschrift: | Journal of Perinatal Medicine, Jg. 39 (2011-09-01), Heft 5, S. 523-527 |
Veröffentlichung: | 2011 |
Medientyp: | academicJournal |
ISSN: | 0300-5577 (print) |
DOI: | 10.1515/JPM.2011.071 |
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