An open label non-comparative case series on the efficacy of an enzyme alginogel.
In: Journal of Wound Care, Jg. 21 (2012), Heft 1, S. 22-27
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Zugriff:
Objective: To evaluate the efficacy of an enzyme alginogel in outpatients with chronic or acute wounds left to heal by secondary intention. Method: This evaluation was a single-centre, single-arm, case series involving 23 patients with wounds of diverse aetiologies treated with the enzyme alginogel (Flaminal; Flen Pharma). The product was applied in accordance with the manufacturer's instructions and wounds were covered with secondary dressings. Treatment was based on a scheduled protocol and patients were assessed at days 14, 30 and 60. Results: Median baseline dimensions for the wounds were surface area 2.6cm 2 and volume 2.8cm 3 . Median wound duration before application of the enzyme alginogel was 292 days, with 16 chronic wounds (78%). Three wounds were clinically infected at baseline; two were negative by day 14 and the third by day 30. After 2 months, wound surface area and volume had decreased, as could be expected. Two adverse events were reported: an allergic reaction in the skin surrounding the wound and transient maceration. Conclusion: The enzyme alginogel facilitated healing in chronic and acute wounds of diverse aetiologies. Additional research is warranted to confirm the clinical utility of the dressings in the management of chronic or acute wounds left to heal by secondary intention. [ABSTRACT FROM AUTHOR]
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Titel: |
An open label non-comparative case series on the efficacy of an enzyme alginogel.
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Autor/in / Beteiligte Person: | Durante, C.M. |
Zeitschrift: | Journal of Wound Care, Jg. 21 (2012), Heft 1, S. 22-27 |
Veröffentlichung: | 2012 |
Medientyp: | academicJournal |
ISSN: | 0969-0700 (print) |
DOI: | 10.12968/jowc.2012.21.1.22 |
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