The Rates of Abnormal Glucose Challenge Tests and Gestational Diabetes in Women Receiving 17α-Hydroxyprogesterone Caproate.
In: American Journal of Perinatology, Jg. 28 (2011-12-01), Heft 10, S. 741-745
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Zugriff:
We compared the rates of abnormal 1-hour glucose challenge tests (GCT) and gestational diabetes (GDM) between women receiving 17α-hydroxyprogesterone caproate (17-P) and women who did not receive 17-P to determine if the effect varies based on the number of doses received or in a group of high-risk obese women. We performed a secondary analysis of a prospective cohort study where women with a history of a previous preterm delivery in the antecedent pregnancy followed at a high-risk clinic were offered 17-P. GCT was performed after the initiation of 17-P, and doses given prior to testing were recorded. Rates of abnormal GCT and GDM were compared between those receiving 17-P (n=67) and controls (n=140). Mean glucose values (112.4 versus 111.3, p=0.8), rate of abnormal GCT (23.9% versus 20%, adjusted odds ratio 1.45, 95% confidence interval 0.7 to 3.0), and rate of GDM (6% versus 8.6%, adjusted odds ratio 1.21, 95% confidence interval 0.3 to 4.5) were similar between groups. In this prospective study, 17-P administration to women at risk of recurrent preterm delivery did not significantly affect glucose tolerance. [ABSTRACT FROM AUTHOR]
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Titel: |
The Rates of Abnormal Glucose Challenge Tests and Gestational Diabetes in Women Receiving 17α-Hydroxyprogesterone Caproate.
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Autor/in / Beteiligte Person: | Wolfe, Katherine ; DeArmond, Christine ; How, Helen ; Henderson, Zsakeba T. ; Sibai, Baha |
Zeitschrift: | American Journal of Perinatology, Jg. 28 (2011-12-01), Heft 10, S. 741-745 |
Veröffentlichung: | 2011 |
Medientyp: | academicJournal |
ISSN: | 0735-1631 (print) |
DOI: | 10.1055/s-0031-1280854 |
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