Effectiveness of 17-α-Hydroxyprogesterone Caproate on Preterm Birth Prevention in Women with History-Indicated Cerclage.
In: American Journal of Perinatology, Jg. 30 (2013-10-01), Heft 9, S. 755-758
academicJournal
Zugriff:
Objective To determine whether 17-α-hydroxyprogesterone caproate (17P) reduces the incidence of preterm birth in women with a history-indicated cerclage. Study Design Retrospective cohort study of women who received a cerclage for a prior preterm birth, analyzed based on exposure to 17P. The primary outcome variable was delivery < 35 weeks. Secondary outcomes were preterm birth < 37, 32, 28, and 24 weeks; interval between cerclage placement and delivery; gestational age at delivery; and infant birth weight. Results Fourteen women received 17P and 80 did not. Baseline characteristics did not differ between these two groups. Preterm delivery at < 35 weeks did not differ between those who received 17P and those who did not (29% versus 15%, p = 0.46). There were no significant differences between the groups for any other outcome. Conclusion 17P does not appear to have an effect on preterm birth < 35 weeks in women with a history-indicated cerclage. [ABSTRACT FROM AUTHOR]
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Titel: |
Effectiveness of 17-α-Hydroxyprogesterone Caproate on Preterm Birth Prevention in Women with History-Indicated Cerclage.
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Autor/in / Beteiligte Person: | Mackeen, A. Dhanya ; Rafael, Timothy J. ; Zavodnick, Jillian ; Berghella, Vincenzo |
Zeitschrift: | American Journal of Perinatology, Jg. 30 (2013-10-01), Heft 9, S. 755-758 |
Veröffentlichung: | 2013 |
Medientyp: | academicJournal |
ISSN: | 0735-1631 (print) |
DOI: | 10.1055/s-0032-1332799 |
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