Meaningful improvement in walking performance after Botulinum Neurotoxin A (BoNT-A) in chronic spastic patients.
In: NeuroRehabilitation, Jg. 34 (2014), Heft 1, S. 185-192
academicJournal
Zugriff:
BACKGROUND: Botulinum neurotoxin A (BoNT-A) may reduce lower limb spasticity but its role in improving walking ability remains to be established. OBJECTIVE: To investigate the efficacy of simultaneous BoNT-A injections into several targeted spastic muscles of different joints on gait speed and on functional gains in gait performance in chronic stroke and MS patients. METHODS: Twenty patients affected by stroke or multiple sclerosis were tested before, one and three months after BoNT-A administration. Gait was evaluated by the 10 Meter Walk Test; patients were stratified into functional ambulation classes accordingly. Spasticity was assessed using the modified Ashworth Scale. RESULTS: At final assessment, spasticity was reduced in hip adductors and ankle plantar-flexors, gait speed improved and, 1/3rd of patients transitioned to a higher ambulation class. The pre-post difference in Level of Spasticity of the hips was a predictor for an increase in gait speed. CONCLUSIONS: A meaningful improvement in walking performance can be obtained in chronic spastic patients after BoNT-A injection into several muscles, specifically the hip adductors. [ABSTRACT FROM AUTHOR]
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Titel: |
Meaningful improvement in walking performance after Botulinum Neurotoxin A (BoNT-A) in chronic spastic patients.
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Autor/in / Beteiligte Person: | Cioncoloni, David ; Taddei, Sabrina ; Bielli, Silvia ; Annunziata, Pasquale ; Mazzocchio, Riccardo |
Zeitschrift: | NeuroRehabilitation, Jg. 34 (2014), Heft 1, S. 185-192 |
Veröffentlichung: | 2014 |
Medientyp: | academicJournal |
ISSN: | 1053-8135 (print) |
DOI: | 10.3233/NRE-131021 |
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