ANAPLASTIČNI KARCINOM ŠTITNJAČE U 17-GODIŠNJE BOLESNICE. (Croatian)

Anaplastic carcinoma of thyroid gland is one of the four most malignant tumors in humans. It appears in one or two patients per million per year. It is very rare in children. A 17-year-old female patient was admitted to the Clinical Department of ENT and Head and Neck Surgery, Split University Hospital Center, for thyroid gland surgery due to rapid growth of a node in the thyroid gland left lobe. Preoperative examination indicated benign nature of changes. Total thyroidectomy with levels VI and VII neck dissection was done. Intraoperative slide of the left lobe was malignant. Positron emission tomography and computed tomography were also done. The fi nding was negative. The patient was examined by an ENT-oncology team and juvenile radiotherapy was administered. It was found to be carcinoma stage IVa according to TNM classifi cation. One year after the operation, the patient was well and had no signs of illness. This case report is a contribution to the existing but scarce knowledge of anaplastic carcinoma of thyroid gland in young patients in the world. [ABSTRACT FROM AUTHOR]

Anaplastični karcinom štitnjače je jedan od četiri najmalignija tumora u čovjeka. Pojavljuje se u jednog do dva bolesnika na milijun ljudi u godini dana. U djece je iznimno rijedak. 17-godišnja bolesnica primljena je u Kliniku za bolesti uha, nosa i grla i kirurgiju glave i vrata u KBC-u Split zbog operacije štitnjače. Ranije joj je nađen nagli porast čvora lijevog režnja štitnjače. Preoperacijska obrada je upućivala na benigan karakter promjena. Napravljena je operacija thyreoidectomia totalis cum dissectione colli regionis VI et VII. Intraoperacijski preparat lijevog režnja štitnjače je bio maligan. Potom se napravio i PET/CT. Nalaz je bio uredan. Bolesnica je upućena otorinolaringološko-onkološkom timu gdje se određuje adjuvantna radioterapija. Stadij bolesti prema TNM klasifi kaciji bio je IVa. Godinu dana nakon operacije bolesnica je dobro, nema znakova bolesti. Ovaj prikaz slučaja je prilog dosadašnjim rijetkim spoznajama o anaplastičnom karcinomu štitnjače u osoba mlađe životne dobi u svijetu. [ABSTRACT FROM AUTHOR]

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