OP086 PREDILECTION SITES AND COMORBIDITIES OF PYODERMA GANGRENOSUM: RESULTS OF A BICENTER STUDY OF 170 PATIENTS.

Aim: Pyoderma gangrenosum (PG) can nowadays be reliably diagnosed with the validated PARACELSUS score. Based on this score, patients with clearly diagnosed PG should be evaluated with regard to the disease characteristics. Method: In this study, data of patients from the University Hospitals of Essen and Erlangen from the last 20 years were retrospectively analysed, in which the diagnosis PG could be clearly confirmed with the help of the PARACELSUS score. Results / Discussion: A total of 170 patients, 49 men (29%) and 121 women (71%) could be included in this analysis. The mean age at first manifestation was 55 years. The predilection sites were identified as the lower legs in 80.6% of the patients and here the extensor sides in 75.2%. Recurrences were seen in 28.8% of the patients, 38.8% in the same and 73.5% in another site. A pathergy phenomenon could be elicited in 42.4% of the patients, 23.6% due to insect bites and 80.6% due to trauma/surgery. Associated systemic diseases were 18.0% inflammatory bowel disease (11.0% Crohn's disease, 7.0% ulcerative colitis), 17.0% neoplasia (13.0% solid tumors, 4.0% hemato-oncologic diseases), 9.0% inflammatory dermatoses (5.0% psoriasis vulgaris, 4.0% hidradenitis suppurativa), and 7.0% rheumatoid arthritis. Conclusion: In this retrospective study, a collective of PG patients is analysed for the first time by means of PARACELSUS score with a high data quality regarding the correctly made diagnosis. It could be shown that especially the anterior sides of the lower sides are the predilection sites for PG. In addition, PG often arises from pathergy phenomena and associated systemic diseases often necessitate interdisciplinary treatment concepts. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Wound Management is the property of Cambridge Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)