New Theranostics Research from National Center for Scientific Research "Demokritos" Discussed (<superscript>177</superscript>Lu-Labeled Iron Oxide Nanoparticles Functionalized with Doxorubicin and Bevacizumab as Nanobrachytherapy Agents against Breast Cancer).
In: Women's Health Weekly, 2024-03-26, S. 691-691
serialPeriodical
Zugriff:
A recent study conducted by researchers at the National Center for Scientific Research "Demokritos" in Athens, Greece, explores the potential of iron oxide nanoparticles as a nanoradiopharmaceutical agent against breast cancer. The nanoparticles were coated with alginic acid and polyethylene glycol and functionalized with the chemotherapeutic agent doxorubicin and the monoclonal antibody bevacizumab. The researchers found that the radiolabeled and non-radiolabeled nanostructures exhibited a high cytotoxic effect against five different breast cancer cell lines in vitro. Additionally, the functionalized radionanoconjugates showed high tumor accumulation and retention at the tumor site when administered intratumorally in tumor-bearing mice. The study concludes that these nanoparticles have the potential to be a promising nanobrachytherapy agent against breast cancer. [Extracted from the article]
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Titel: |
New Theranostics Research from National Center for Scientific Research "Demokritos" Discussed (<superscript>177</superscript>Lu-Labeled Iron Oxide Nanoparticles Functionalized with Doxorubicin and Bevacizumab as Nanobrachytherapy Agents against Breast Cancer).
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Zeitschrift: | Women's Health Weekly, 2024-03-26, S. 691-691 |
Veröffentlichung: | 2024 |
Medientyp: | serialPeriodical |
ISSN: | 1078-7240 (print) |
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