Study Findings from Department of Surgery Update Knowledge in Reperfusion Injury (Protective effects of cyclosporine and its analog NIM-811 in a murine model of hepatic ischemia-reperfusion injury).
In: Medical Devices & Surgical Technology Week, 2024-04-21, S. 504-504
serialPeriodical
Zugriff:
A study conducted by the Department of Surgery explores the protective effects of cyclosporine and its analog NIM-811 in a murine model of hepatic ischemia-reperfusion injury (IRI). The liver is vulnerable to IRI during hepatic surgery or liver transplantation, which can lead to mitochondrial dysfunction and cell death. The researchers tested the effects of cyclosporine and NIM-811 on warm hepatic IRI in mice and found that both agents significantly reduced alanine transaminase levels and histological injury scores. These findings have potential implications for mitigating IRI during liver transplantation and resection. [Extracted from the article]
Copyright of Medical Devices & Surgical Technology Week is the property of NewsRx and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Study Findings from Department of Surgery Update Knowledge in Reperfusion Injury (Protective effects of cyclosporine and its analog NIM-811 in a murine model of hepatic ischemia-reperfusion injury).
|
---|---|
Zeitschrift: | Medical Devices & Surgical Technology Week, 2024-04-21, S. 504-504 |
Veröffentlichung: | 2024 |
Medientyp: | serialPeriodical |
ISSN: | 1537-1409 (print) |
Sonstiges: |
|