Spatial Transcriptomics of Meningeal Inflammation Reveals Variable Penetrance of Inflammatory Gene Signatures into Adjacent Brain Parenchyma (Updated April 17, 2024).
In: Health & Medicine Week, 2024-05-03, S. 6052-6052
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Zugriff:
A recent study conducted on a mouse model of autoimmune meningeal inflammation aimed to understand the connection between meningeal inflammation and grey matter pathology in the brain. The researchers used MRI-guided spatial transcriptomics to analyze the transcriptional signature in areas of meningeal inflammation and the adjacent brain tissue. They found increased activity of inflammatory signaling pathways in the inflamed areas, but only a subset of these pathways were active in the adjacent brain tissue. This study provides valuable data and highlights potential pathways involved in the development of grey matter pathology. However, it is important to note that this research has not yet undergone peer review. [Extracted from the article]
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Spatial Transcriptomics of Meningeal Inflammation Reveals Variable Penetrance of Inflammatory Gene Signatures into Adjacent Brain Parenchyma (Updated April 17, 2024).
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Zeitschrift: | Health & Medicine Week, 2024-05-03, S. 6052-6052 |
Veröffentlichung: | 2024 |
Medientyp: | serialPeriodical |
ISSN: | 1531-6459 (print) |
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